Granada Crystallization Box
Granada Crystallization Box ®
FOR PROTEIN CRYSTALLIZATION
Granada Crystallization Box® (GCB) is a simple device to crystallize protein and other biological macromolecules by counter-diffusion method. GCB consists of 4 elements made of polystyrene:
- A reservoir to introduce the gel
- A guide to hold capillaries
- A cover
- A holder to maintain the boxes
The GCB has been designed to be used in four different ways:
- To grow crystals inside gels under diffusion controlled mass transport.
- To grow protein crystals inside capillaries with un-gelled precipitating agent by the counter-diffusion technique.
- To grow protein crystals inside capillaries with gelled precipitating agent by the counter-diffusion technique.
- To grow protein crystals inside capillaries by the batch method.
- Crystallization is performed under diffusion-controlled mass transport.
The role of viscous fluids, gels and/or micro-gravity is enhanced by using capillary volumes.
- Reduces the consumption of macromolecule:
From 500 nanoliters to 100 nanoliters of protein solutions depending on the inner diameter of the capillaries.
- Automatically searches for the optimal crystallization conditions:
One capillary scans the same precipitation region than hundreds of drops.
- Easy and safe transport to x-ray diffraction facilities
Transport your precious crystals in your pocket!
- Full visualization of the crystallization process
- In situ x-ray crystallography:
Crystals grow inside x-ray capillaries
If desired, no handling of crystals
Usable for cryo-crystallography
Triana Science & Technology offers GCBs in packages of 20 boxes
Price per package
GCB - A - 20
User guide of Granada Crystallization Box® (GCB):
To make an order, just send us an email to
with a list of the required products and services you need or from the menu "orders".
- J.M. García-Ruiz, Counterdiffusion Methods for Macromolecular Crystallization. Methods in Enzymology, Vol. 368 (2003) 130-154.
- Granada Crystallisation Box: a new device for protein crystallisation by counter-diffusion techniques. Garcia-Ruiz JM, Gonzalez-Ramirez LA, Gavira JA, Otalora F. Acta Crystallogr D Biol Crystallogr. 2002 Oct;58 (Pt 10 Pt 1):1638-42.